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Figure 3 | BMC Immunology

Figure 3

From: Maternal immunization with ovalbumin prevents neonatal allergy development and up-regulates inhibitory receptor FcγRIIB expression on B cells

Figure 3

Effect of maternal immunization with OVA on the immune response of nonimmunized or immunized neonates. Neonate pups (3 d-o) from control or immune mothers were immunized or not with OVA and evaluated (20 d-o) for: (A) IgG1, IgG2a and IgM by ELISA; (B) anti-OVA IgE Ab levels by PCA reaction; (C) intracellular cytokines of splenic B cells (B220+) or (d) CD4+ T cells after 24 h incubation with 10 μg/mL brefeldin A by flow cytometry. The results represent the mean ± SEM of 12 mice per group. *P ≤ 0.05 compared to offspring from nonimmunized mothers, # P ≤ 0.05 compared to nonimmunized offspring from control mothers, • P ≤ 0.05 compared to control offspring from immune mothers.

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