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Figure 6 | BMC Immunology

Figure 6

From: Maternal immunization with ovalbumin prevents neonatal allergy development and up-regulates inhibitory receptor FcγRIIB expression on B cells

Figure 6

Effect of passive IgG transference to pregnant mice on neonatal B cell FcγRIIb expression. Nonimmunized pregnant mice were injected with IgG from nonimmunized or immunized mothers. Nonimmunized neonates were evaluated (3 d-o) for: (A) CD80, CD86, CD40, and CD23 molecule expression on splenic B cells (B220+) and (B) B cell FcγRIIb expression (B220+IgM+) by flow cytometry. Histogram of FcγRIIb expression on B cells of offspring from immunized (shaded histogram, MFI in bold numbers) or nonimmunized mothers (white histogram, MFI in light numbers). The results represent the mean ± SEM of 6 mice per group. * P ≤ 0.05 compared to offspring from nonimmunized mothers.

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BMC Immunology

ISSN: 1471-2172

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