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Figure 3 | BMC Immunology

Figure 3

From: Anti-infective activity of apolipoprotein domain derived peptides in vitro: identification of novel antimicrobial peptides related to apolipoprotein B with anti-HIV activity

Figure 3

Antiviral and antibacterial activity of apoBdprelated peptides. (A) A peptide consisting of a tandem repeat peptide of the naturally occurring apoB3359-3367 sequence has limited antiviral activity which is enhanced in the apoBdpL/R modified sequence, though (B) antibacterial activity was not measurable for both. (C) ApoBdpL/R has comparable antiviral activity to apoEdp though (D) does not share its strong antibacterial activity. (E) The Trp-substituted apoBdpL/R-W peptide has stronger antiviral activity and (F) shows similar antibacterial activity. Values shown are HSV1 infectivity after plaque reduction assay in Vero cells or turbidity of Pseudomonas aeruginosa; typical data are shown; bars indicate standard error.

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BMC Immunology

ISSN: 1471-2172

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