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Figure 4 | BMC Immunology

Figure 4

From: Anti-infective activity of apolipoprotein domain derived peptides in vitro: identification of novel antimicrobial peptides related to apolipoprotein B with anti-HIV activity

Figure 4

Reduction of antiviral and antibacterial activity of apoEdpL/R-W peptides after alteration of Arg-Lys-Arg repeated motif. Substitution of the repeated Arg-Lys-Arg motif within apoBdpL/R-W for Arg-Arg-Arg (apoBdpL/R-WR) or Lys-Lys-Lys (apoBdpL/R-WK) reduces (A) antiviral activity or (B) antibacterial activity. Values shown are HSV1 infectivity after plaque reduction assay in Vero cells or turbidity of Pseudomonas aeruginosa; typical data are shown; bars indicate standard error.

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