Differential effects of Paclitaxel on dendritic cell function

BMC Immunology

Table 2 Microarray analysis of DC exposed to LPS 1 μg/ml or paclitaxel 100 μM for 2 hours.

	Name	Accession number	Taxol	LPS
Cytokines	IL6	NM_000600	0.625	13.75
	IL1B	NM_000576	0.57	21.4
	IL10	NM_000572	0.14	1.3
	IL18	NM_001562	0.44	4.77
	IL1A	NM_000575	2.33	2.5
	TGFβ	NM_000660	0.5	0.43
	CXCl12	NM_199168	1.428	42.3
Cell cycle	CCND1	NM_053056	0.286	0.11
	p21	NM_000389	0.875	3.125
	ASK	NM_006716	0.833	0.417
	PCNA	NM_002592	0.6	1.25
Apoptosis	API4	NM_001012271	0.4	1
	FAS	NM_000043	0.667	6.22
	CASP8	NM_033356	1.2	0.45
	TNFRSF11B	NM_002546	0.1	2.2
	CASP3	NM_004346	0.7	3.3
	TNFα	NM_000594	0.4	3
	FASLG	NM_000639	0.375	5.625
Receptors	ICAM1	NM_000201	0.667	3.77
	TLR2	NM_003264	0.413	3.45
	TLR4	NM_003266	0.769	0.078
	CXCR4	NM_001008540	1	2

(Bold signifies upregulation)
Data shown is for samples where gene expression differed from untreated
cells (where P < 0.01). All microarray data was deposited in Array express; accession number E-MEXP-2465, experiment name Pandha DC taxol.

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