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Table 2 Microarray analysis of DC exposed to LPS 1 μg/ml or paclitaxel 100 μM for 2 hours.

From: Differential effects of Paclitaxel on dendritic cell function

  Name Accession number Taxol LPS
Cytokines IL6 NM_000600 0.625 13.75
  IL1B NM_000576 0.57 21.4
  IL10 NM_000572 0.14 1.3
  IL18 NM_001562 0.44 4.77
  IL1A NM_000575 2.33 2.5
  TGFβ NM_000660 0.5 0.43
  CXCl12 NM_199168 1.428 42.3
Cell cycle CCND1 NM_053056 0.286 0.11
  p21 NM_000389 0.875 3.125
  ASK NM_006716 0.833 0.417
  PCNA NM_002592 0.6 1.25
Apoptosis API4 NM_001012271 0.4 1
  FAS NM_000043 0.667 6.22
  CASP8 NM_033356 1.2 0.45
  TNFRSF11B NM_002546 0.1 2.2
  CASP3 NM_004346 0.7 3.3
  TNFα NM_000594 0.4 3
  FASLG NM_000639 0.375 5.625
Receptors ICAM1 NM_000201 0.667 3.77
  TLR2 NM_003264 0.413 3.45
  TLR4 NM_003266 0.769 0.078
  CXCR4 NM_001008540 1 2
  1. (Bold signifies upregulation)
  2. Data shown is for samples where gene expression differed from untreated
  3. cells (where P < 0.01). All microarray data was deposited in Array express; accession number E-MEXP-2465, experiment name Pandha DC taxol.