Figure 1

Salmon STAT1 protein harbors conserved domains and sequences. The NCBI conserved domains database and ClustalW alignment was combined to depict the schematic presentation of STAT1. Abbreviations: ND = amino-terminal domain, DNAD = DNA-binding domain, SH2 = Src Homology 2 domain, TAD = transcriptional activation domain, NES = nuclear export signal, NLS = nuclear localization signal, ss = Atlantic salmon, rt = rainbow trout, hs = human. Asterisks indicate conserved residues with importance for the functional activity within the domains.