Table 2 Total number of PPE18 epitopes predicted to bind each allele by the five programs that predicted epitope binding for the largest number of DRB1 alleles and the number and percentage of unconserved epitopes
| Â | No of total predicted epitopes | No of unconserved epitopes (%) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
DRB1 Allele | ARB | ProPred | RankPep | NetMHCII | NetMHCIIpan | ARB | ProPred | RankPep | NetMHCII | NetMHCIIpan |
0101 | 133 | 17 | 30 | 104 | 77 | 83 (62) | 9 (53) | 20 (67) | 61 (59) | 46 (60) |
0301 | 17 | 8 | 0 | 0 | 1 | 13 (76) | 4 (50) | 0 (N/A) | 0 (N/A) | 1 (100) |
0401 | 33 | 12 | 33 | 18 | 7 | 20 (61) | 8 (67) | 23 (70) | 13 (72) | 7 (100) |
0404 | 47 | 15 | 5 | 14 | 10 | 30 (64) | 10 (67) | 5 (100) | 14 (71) | 8 (80) |
0405 | 29 | 13 | 2 | 14 | 13 | 20 (69) | 8 (62) | 1 (50) | 9 (64) | 9 (69) |
0701 | 31 | 7 | 6 | 16 | 28 | 22 (71) | 5 (71) | 4 (67) | 11 (69) | 19 (68) |
0802 | 8 | 7 | Â | 0 | 1 | 7 (87) | 6 (86) | Â | 0 (N/A) | 1 (100) |
0901 | 35 | Â | 3 | 22 | 21 | 18 (51) | Â | 3 (100) | 13 (59) | 14 (67) |
1101 | 16 | 13 | 15 | 5 | 4 | 12 (75) | 10 (77) | 6 (40) | 3 (60) | 3 (75) |
1301 | Â | 7 | 0 | Â | 1 | Â | 6 (86) | 0 (N/A) | Â | 1 (100) |
1302 | 18 | 5 | 0 | 24 | 2 | 13 (72) | 4 (80) | 0 (N/A) | 16 (67) | 2 (100) |
1501 | 14 | 10 | 1 | 12 | 7 | 10 (71) | 8 (80) | 1 (100) | 6 (50) | 5 (71) |