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Figure 3 | BMC Immunology

Figure 3

From: The antigen presentation function of bone marrow-derived mast cells is spatiotemporally restricted to a subset expressing high levels of cell surface FcεRI and MHC II

Figure 3

Block of surface FcεRI-mediated antigen focusing and presentation of anti-DNP IgE/TNP-OVA by ragweed-specific IgE. BMMC were preincubated with anti-ragweed IgE at 100 μg/ml for one hr, washed and, followed by addition of IgE/TNP-OVA complexes, and coincubated with 3Do-54.8. Levels of IL-2 in 72 hr supernatants were determined by stimulating 3H-thymidine incorporation and proliferation of IL-2 dependent NK-3 cells as described in Material and methods.

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