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Table 3 Concentration (pg/ml) of 20 biomarkers measured 12 months after BCG vaccination of UK adolescents (values given are group median and interquartile range calculated after individual measurements were background corrected (PPD-stimulated - unstimulated values); n = 12)

From: Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining

Biomarker

12 months post vaccination

IL-1α

1710.0 (949.2-2008.0)

IL-1β

4.5 (1.6-10.1)

IL-2

8.2 (5.3-14.8)

IL-4

1.6 (1.6-1.8)

IL-5

1.6 (1.6-4.7)

IL-6

383.0 (198.7-1653.0)

IL-7

48.4 (36.2-95.6)

IL-8

6030.0 (521.8-11935.0)

IL-10

12.7 (10.2-22.2)

IL-12p70

1.9 (1.6-5.9)

IL-13

1.6 (1.6-6.9)

IL-15

1.6 (1.6-1.6)

IL-17

22.0 (3.0-37.8)

IFNγ

79.0 (37.9-239.1)

TNF-α

38.9 (26.9-140.0)

GM-CSF

147.7 (88.7-289.0)

G-CSF

3.8 (1.6-10.0)

MIP-1α

69.9 (27.0-279.3)

IP-10

4240.0 (2645.0-7670.0)

EOTAXIN

29.9 (23.7-37.1)