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Table 1 24 h Survival status in BoNT/B-mouse neutralization assaya.

From: Adenovirus F protein as a delivery vehicle for botulinum B

Vaccination Groupb

Sera Titerc

%Survivald

p-valuee

Naïve

0

0

-

Hcβtre/B + CT

19.5 ± 0.5

100

< 0.05

Hcβtre-Ad2F + CT

19.8 ± 0.2

100

< 0.05

  1. a Pooled sera from nasally vaccinated or naive mice incubated for 1 h with 2.0
  2. LD50 of BoNT/B in PBS-0.2% gelatin and then injected into naive mice.
  3. b Source of sera used.
  4. c Endpoint titer for Hc/B in pooled sera (10 mice/group).
  5. d Survival of BoNT/B-challenged mice after 24 h.
  6. e p-value determined by Kaplan-Meier method.
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BMC Immunology

ISSN: 1471-2172

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