Figure 1

Relative levels of total T cells and T cell subsets (CD3⁺CD8⁺ and CD3⁺CD4⁺) in AML patients receiving intensive chemotherapy. T cell levels were investigated for patients with untreated AML (AML, n = 16), patients with chemotherapy-induced cytopenia (Cytopenia, n = 16; the first cohort of patients) and during hematopoietic reconstitution after chemotherapy (Reconstitution, n = 6); these results were compared with healthy controls (n = 30). A. The levels of circulating CD3⁺ T cells are presented as the percentages of total viable leukocytes (left panel) or total lymphocytes (right panel). B. The levels CD8⁺ (T_C) and CD4⁺ (i.e. CD3⁺CD8^- cells referred to as CD4⁺ T_H cells) T cell levels are presented as the percentages of positive cells among total CD3⁺ lymphocytes. All results are presented as median (horizontal line), 25^th to 75^th percentiles (boxes) and variation range (whiskers). The percentages of total T cells or T cell subsets did not show any age-dependent variation among the healthy controls. Statistically significant differences are indicated at the top of the figures (Mann-Whitney test).