Peripheral blood levels of T
1 and T
17 cells; analysis of covariation between various T cell subsets and differences between males and females. A. Bivariate regression analysis was used to analyze the correlations between TH1/TC1 and TH1/TH17 cell subsets in AML patients with untreated disease (AML, n = 16) and patients with chemotherapy-induced cytopenia (Cytopenia, n = 16; the first cohort of patients); these results were compared with healthy controls (n = 30). The levels are presented as the percentage of each cell type among the parent population, i.e. TC1 cells among CD8+ T cells, TH1 and TH17 cells among CD8- T cells. The p- and r2-values for each analysis are indicated in each figure. B. Analysis of TH1 and TH17 levels in male and female healthy controls (all controls and those controls older than 50 years) and patients with untreated AML patients. The levels are presented as the percentage of each cell type among CD8- T cells. All results are presented as the median (line within the box), 25th to 75th percentiles (box) and variation ranges (whiskers), are presented as percentages of parent. P-values are given in each figure.