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Figure 1 | BMC Immunology

Figure 1

From: Changes in colon gene expression associated with increased colon inflammation in interleukin-10 gene-deficient mice inoculated with Enterococcus species

Figure 1

Summary of the colon histological injury score (HIS) in Il10-/-and C57 mice in response to various treatments. Data represent mean ± SD for 5 mice fed the AIN-76A diet, and housed in specific pathogen free (SPF) or conventional (C) conditions, or housed in conventional conditions and orally inoculated with 12 Enterococcus strains (EF), with conventional intestinal flora from normal C57 mice (CIF), or a 1:1 combination (EF·CIF). Asterisks denote Il10-/-mice with values significantly different (*P < 0.05, ***P < 0.01) from C57 mice in the same treatment group, while the "†" symbol denotes Il10-/-mice with values significantly (P < 0.05) different from Il10-/-mice under SPF conditions for the same histological parameter. One Il10-/-mouse in the CIF treatment group died during the course of the trial. An autopsy was unable to unequivocally establish the cause of death.

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