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Table 4 The cytotoxicity of MNCs from peritoneal tissue was significantly enhanced after repeated vaccinations.

From: Tumor vaccine composed of C-class CpG oligodeoxynucleotides and irradiated tumor cells induces long-term antitumor immunity

Group 2 × 90d* 3 × 90d* 2 × 60d** 3 × 60d** 2 × 30d*** 3 × 30d***
p-value a 0.024 0.004 0.056 0.004 0.006 <0.001
  1. a p-value: group compared to group vaccinated once 90, 60 or 30 days before tumor challenge
  2. * vaccination started 90 days before the injection of viable tumor cells; the vaccine was applied once (1×), twice (2×) or three times (3×) in 15 days interval
  3. ** vaccination started 60 days before the injection of viable tumor cells; the vaccine was applied once (1×), twice (2×) or three times (3×) in 15 days interval
  4. *** vaccination started 30 days before the injection of viable tumor cells; the vaccine was applied once (1×), twice (2×) or three times (3×) in 15 days interval, except for the last - third vaccination, which was performed 7 days after second vaccination