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Figure 8 | BMC Immunology

Figure 8

From: Serum lipoproteins attenuate macrophage activation and Toll-Like Receptor stimulation by bacterial lipoproteins

Figure 8

Effect of human serum, LDL, triglyceride emulsion, and apoB on the production of IL-8 by HEK-293 cell line expressing human TLR1/2, upon Mip and OspA activation. Null and hTLR1/2 cells were stimulated with 1 μg/ml Mip or OspA for 24 h in the presence or absence of serum lipids. Culture supernatants were collected and IL-8 content was analyzed. Background values (unstimulated) were subtracted. Each value represents the mean ± SD of triplicates from two experiments. **: p < 0.005, ***: p < 0.0001 determined by comparison with bacterial component alone using Student's t test.

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