Associations between SNPs in candidate immune-relevant genes and rubella antibody levels: a multigenic assessment

BMC Immunology

Table 1 Characteristics of the study population and their associations with rubella-specific IgG antibody levels (reported in IU/ml).

Variable	Level	Number of subjects	Median	Q1 - Q3^a	P-value^b
Overall		714	34.5	19.2 - 63.7
Age at enrollment (years)	11-13	212	37.0	19.1 - 67.1	0.967
	14-15	190	34.8	19.4 - 58.5
	16-17	200	33.3	19.2 - 70.2
	18-19	112	34.5	19.2 - 57.9
Age at first rubella vaccination (months)	≤14	89	35.4	19.6 - 59.9	0.556
	15	384	31.4	19.0 - 62.2
	16-17	119	41.2	18.9 - 72.6
	≥18	122	39.9	21.8 - 66.2
Age at second rubella vaccination (years)	≤5	205	27.6	16.6 - 55.3	0.001
	6-10	109	37.0	20.5 - 69.6
	11	122	34.9	18.9 - 65.4
	≥12	278	39.9	22.1 - 69.7
Gender	Female	336	39.9	20.0 - 69.7	0.009
Gender	Male	378	30.9	18.3 - 56.7
Race	Other	65	33.4	17.7 - 62.9	0.903
Race	White	649	34.5	19.2 - 63.7

Notes:
^a Q1 and Q3 represent the first (25^th percentile) and third (75^th percentile) quartiles, respectively.
^b p-value represents a test of the null hypothesis that there are no differences in the level of rubella antibody IgG levels among the categories represented.

ISSN: 1471-2172