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Figure 1 | BMC Immunology

Figure 1

From: Macrophage migration inhibitory factor regulates interleukin-6 production by facilitating nuclear factor-kappa B activation during Vibrio vulnificus infection

Figure 1

The production of serum proinflammatory cytokines in V. vulnificus -infected mice. BALB/c mice were intraperitoneally infected with V. vulnificus (Vv05191; 1 × 106 CFU) for the indicated time periods. ELISA was used to determine serum concentrations of MIF (A), IL-6 (B), and TNF-α (C). (D) With or without ISO-1 (25 mg/kg) pretreatment for 0.5 h, ELISA was used to determine the serum concentrations of IL-6 and TNF-α in V. vulnificus-infected mice at 6 h post-infection. Data are the means ± SD from three individual experiments. *P < 0.05 vs. non-infected controls or V. vulnificus infection only.

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