The gastrointestinal nematode Trichostrongylus colubriformis down-regulates immune gene expression in migratory cells in afferent lymph

Table 1 Numbers of ESTs significantly modulated during immunising and challenge infections (P < 0.05)

Immunising Infection
	Unique ESTs	Comparison^a
		PI_I1	PI_I2	PI_I3	I1_I2	I1_I3	I2_I3
ESTs with RefSeq	2213	269	743	718	1353	650	193
Modulated more than 1.3-fold (up or down)	549	-	-	-	-	-	-
Down regulated (> 1.3-fold)	-	20	109	115	277	81	8
Up regulated (> 1.3-fold)	-	18	32	58	62	33	8
Challenge Infection
	Unique ESTs	Comparison ^a
		PI_C1	PI_C2	PI_C3	C1_C2	C1_C3	C2_C3
ESTs with RefSeq	1066	285	430	498	152	192	309
Modulated more than 1.3-fold (up or down)	373	-	-	-	-	-	-
Down regulated (> 1.3-fold)	-	55	105	122	23	23	47
Up regulated (> 1.3-fold)	-	32	42	54	14	16	32

ISSN: 1471-2172