Figure 4

Regulatory effects of IL-33 in LPS-activated human macrophages. (A) CCL18 transcript levels in primary macrophages exposed to cytokine or TLR ligand alone or in combination with 10 ng/ml of IL-33. (B) CCL3 transcript levels in primary macrophages exposed to cytokine or TLR ligand alone or in combination with 10 ng/ml of IL-33. Results are expressed as fold increase in transcript levels compared with levels of these transcripts in human macrophages exposed to media alone (i.e. control condition). Data are expressed as mean ± SEM and are representative of experiments performed with 4 donor macrophage lines.