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Table 5 B/I activated tDLN track preferentially to 4T1 tDLN and persist

From: Phenotype, functions and fate of adoptively transferred tumor draining lymphocytes activated ex vivo in mice with an aggressive weakly immunogenic mammary carcinoma

Tumor

 

MethA

4T1

No Tumor

Day 3

Spleen

2.1%

10.4%

2.4%

Day 6

Spleen

0.5%

3.3%

1.7%

Day 3

tDLN

3.1%

9.2%

_____

Day 6

tDLN

2%

10.1%

_____

  1. Naïve mice or mice with established MethA or 4T1 flank tumors were treated with CYP on day 9 followed by AIT with 50 × 106 CFSE-stained B/I activated 4T1 tDLN (on day 10). At 3 and 6 days after AIT, the tDLN and spleens were harvested and analyzed by flow cytometry for CFSE + cells. This is a representative experiment of 3 replicates.