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Table 2 Laboratory parameters of healthy non-pregnant and pregnant women and preeclamptic patients

From: Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array

  Healthy non-pregnant women (n = 59) Healthy pregnant women (n = 60) Preeclamptic patients (n = 60)
Serum BUN level (mmol/l) 4.1 (3.5-4.8) 2.8 (2.0-3.3)b 3.5 (2.7-4.2)a,c
Serum creatinine level (μmol/l) 66 (61-72) 49 (42-56)b 63 (55-71)d
Serum bilirubin level (μmol/l) 9.3 (6.6-12.4) 5.4 (4.0-6.8)b 7.3 (5.7-8.9)a,c
Serum AST activity (U/l) 17 (15-20) 19 (17-21) 19 (15-25)
Serum ALT activity (U/l) 14 (12-17) 12 (10-15)a 16 (11-23)c
Serum LDH activity (U/l) 154 (128-170) 158 (138-169) 192 (153-225)b,d
Serum CRP level (mg/l) 0.7 (0.5-1.8) 3.6 (1.7-6.6)b 6.8 (2.7-12.1)b,c
Plasma VWF:Ag level (%) 70.0 (60.2-87.3) 152.6 (112.7-199.0)b 184.8 (139.9-243.1)b,c
Plasma fibronectin level (g/l) n.m. 0.37 (0.31-0.47) 0.58 (0.41-0.82)d
Plasma malondialdehyde level (nmol/ml) n.m. 15.4 (8.8-18.6) 18.3 (15.6-20.4)c
Plasma cell-free fetal DNA level (pg/μl) n.m. 0.002 (0.0-0.172) 0.082 (0.033-0.292)‡,c
  1. Data are presented as median (25-75 percentile)
  2. n.m.: not measured; BUN: blood urea nitrogen; AST: aspartate aminotransferase; ALT: alanine aminotransferase; LDH: lactate dehydrogenase; CRP: C-reactive protein; VWF:Ag: von Willebrand factor antigen; DNA: deoxyribonucleic acid
  3. n = 19
  4. n = 33
  5. a p < 0.05 versus healthy non-pregnant women
  6. b p < 0.001 versus healthy non-pregnant women
  7. c p < 0.05 preeclamptic patients versus healthy pregnant women
  8. d p < 0.001 preeclamptic patients versus healthy pregnant women