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Table 2 Laboratory parameters of healthy non-pregnant and pregnant women and preeclamptic patients

From: Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array

 

Healthy non-pregnant women (n = 59)

Healthy pregnant women (n = 60)

Preeclamptic patients (n = 60)

Serum BUN level (mmol/l)

4.1 (3.5-4.8)

2.8 (2.0-3.3)b

3.5 (2.7-4.2)a,c

Serum creatinine level (μmol/l)

66 (61-72)

49 (42-56)b

63 (55-71)d

Serum bilirubin level (μmol/l)

9.3 (6.6-12.4)

5.4 (4.0-6.8)b

7.3 (5.7-8.9)a,c

Serum AST activity (U/l)

17 (15-20)

19 (17-21)

19 (15-25)

Serum ALT activity (U/l)

14 (12-17)

12 (10-15)a

16 (11-23)c

Serum LDH activity (U/l)

154 (128-170)

158 (138-169)

192 (153-225)b,d

Serum CRP level (mg/l)

0.7 (0.5-1.8)

3.6 (1.7-6.6)b

6.8 (2.7-12.1)b,c

Plasma VWF:Ag level (%)

70.0 (60.2-87.3)

152.6 (112.7-199.0)b

184.8 (139.9-243.1)b,c

Plasma fibronectin level (g/l)

n.m.

0.37 (0.31-0.47)

0.58 (0.41-0.82)d

Plasma malondialdehyde level (nmol/ml)

n.m.

15.4 (8.8-18.6)

18.3 (15.6-20.4)c

Plasma cell-free fetal DNA level (pg/μl)

n.m.

0.002 (0.0-0.172)

0.082 (0.033-0.292)‡,c

  1. Data are presented as median (25-75 percentile)
  2. n.m.: not measured; BUN: blood urea nitrogen; AST: aspartate aminotransferase; ALT: alanine aminotransferase; LDH: lactate dehydrogenase; CRP: C-reactive protein; VWF:Ag: von Willebrand factor antigen; DNA: deoxyribonucleic acid
  3. n = 19
  4. n = 33
  5. a p < 0.05 versus healthy non-pregnant women
  6. b p < 0.001 versus healthy non-pregnant women
  7. c p < 0.05 preeclamptic patients versus healthy pregnant women
  8. d p < 0.001 preeclamptic patients versus healthy pregnant women