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Figure 3 | BMC Immunology

Figure 3

From: Iloprost modulates the immune response in systemic sclerosis

Figure 3

Iloprost reduces Tregs. PBMCs isolated from SSc patients at baseline and after treatment with iloprost (5 days of daily treatment, 28 days since the last infusion) were analysed by flow cytometry to evaluate Tregs (CD4+/CD25bright/FoxP3+ lymphocytes) and by real time PCR to evaluate FoxP3 expression. A. Graph shows the percentage of Tregs in PBMCs. Bars represent mean and SD for all the patients, p values were calculated with Student's paired t test, significant values are displayed. B. Graph shows FoxP3 expression in PBMCs from patients at baseline and after treatment. The FoxP3 expression was corrected for expression of the housekeeping gene β actin. Bars represent mean and SD for all the patients, p values were calculated with Student's paired t test, significant values are displayed.

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