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Figure 5 | BMC Immunology

Figure 5

From: Maternal allergen immunisation to prevent sensitisation in offspring: Th2-polarising adjuvants are more efficient than a Th1-polarising adjuvant in mice

Figure 5

Secretion of cytokines from spleen cells from 9 week-old immunised offspring. Cytokine response in offspring from mothers immunised with ovalbumin (OVA) combined with either Al(OH)3, pertussis toxin, or CpG. Spleen cells were incubated alone or in combination with the allergen OVA and cytokine secretion were measured after 72 hours (unstimulated) and 6 days (unstimulated or stimulated with OVA). Ten offspring per group of mother were included. The concentrations of IL-5 (A, B, C), IL-10 (D, E, F) and IFNγ (G, H, I) are given in pg/ml and the median values are indicated by a line, * denotes a statistically significant difference compared to the OVA group, p < 0.05.

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