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Table 2 OVA-specific antibody levels in mothers 10 days after delivery (during lactation period).

From: Maternal allergen immunisation to prevent sensitisation in offspring: Th2-polarising adjuvants are more efficient than a Th1-polarising adjuvant in mice

 

Al(OH)3 mothers

PT Mothers

CpG mothers

Naive mothers

IgE

2150

(1673-2360)*

4094

(2261-4953)*

90

(90-90)

90

(90-90)

IgG1

2.5 × 108

(1.6 × 108-4.2 × 108)*

3.0 × 108

(2.4 × 108-4.4 × 108)*

4.2 × 107

(2.1 × 107-7.8 × 107)

2.0 × 106

(2.0 × 106-2.1 × 106)

IgG2a

1.9 × 105

(9.9 × 104-3.3 × 105)

2.1 × 105

(9.6 × 104-10 × 105)

1.5 × 106

(9.6 × 105-5.2 × 106)

2.6 × 105

(1.1 × 105-1.2 × 106)

  1. Mothers were immunised during pregnancy with either OVA + Al(OH)3, OVA + pertussis toxin (PT), OVA + CpG, or were not unimmunised. OVA-specific antibody levels are given as medians with 25- and 75-percentiles (AU/ml). * p < 0.05.
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BMC Immunology

ISSN: 1471-2172

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