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Figure 4 | BMC Immunology

Figure 4

From: Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide

Figure 4

MBL attenuates allogeneic T cell proliferation induced by LPS-primed MDCs. T cells obtained from PBMC (2 × 105 cells/well) were co-cultured with either imMDCs, MBL-preincubated and LPS-primed MDCs, HSA-preincubated and LPS-primed MDCs, or LPS-primed MDCs at the indicated DC:T cell ratios. Anti-MBL pAb was used to demonstrate the specificity of the MBL-induced response. Proliferation of T cells was determined after 4 days of culture by 3H-thymidine uptake. Data given as mean ± S.D. of triplicate samples are representative of four independent experiments. *P < 0.05 as compared to LPS-stimulated group.

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