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Figure 6 | BMC Immunology

Figure 6

From: Ketamine inhibits tumor necrosis factor secretion by RAW264.7 murine macrophages stimulated with antibiotic-exposed strains of community-associated, methicillin-resistant Staphylococcus aureus

Figure 6

TNF suppression by ketamine was tested at concentrations of 10 μM, 50 μM, 100 μM and 150 μM in the presence of vancomycin at 20 μg/mL and RAW264 macrophage stimulation with either LAC (upper panel) or MW2 (lower panel) CA-MRSA strains. Bacteria were added at a final concentration of 105 to107 CFU/mL (retrospective confirmation) in the presence of vancomycin at 20 μg/mL. The inoculation time was 18 hours. Results are depicted as percentile reduction with 95% confidence intervals shown, i.e., the percent of TNF reduction that occurs after the specific concentration of ketamine was added.

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