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Figure 6 | BMC Immunology

Figure 6

From: Multifaceted effects of synthetic TLR2 ligand and Legionella pneumophilia on Treg-mediated suppression of T cell activation

Figure 6

Treg suppression assay using wildtype and TLR-2 knockout cell types. (A) Suppression assays were performed with different combinations of wildtype and TLR2-deficient Treg, Teff or APCs. In each experiment only one of the three cell types was derived from wild type mice and thus able to respond to Pam3Cys. Data show that Pam3Cys released Treg-mediated suppression in every condition and hence affected all cell types directly. (B) Suppression assays with all cells being either TLR2 knockout or wildtype show maximal suppression and maximal release from Treg mediated suppression, respectively. Representative results of 2 experiments are shown. The error bars represent standard deviations of duplicate measurements.

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BMC Immunology

ISSN: 1471-2172

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