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Table 2 The viability of MDDC and expression of some surface markers on the mature MDDC treated with FL-AFP at different concentration

From: Immunoregulatory effects of AFP domains on monocyte-derived dendritic cell function

 

Cell viability (%)

Surface marker expression (%)

 

PI+

PI-

CD80+

CD86+

CD83+

Non Treated

1.7 ± 1.0

98.3 ± 1.0

92.3 ± 5.8

99.4 ± 0.6

75.6 ± 24.1

FL-AFP 1.56 μg/ml

2.4 ± 1.7

97.6 ± 1.7

77.1 ± 20.1

98.8 ± 1.1

48.4 ± 21.7

FL-AFP 3.12 μg/ml

3.3 ± 2.2

96.7 ± 2.2

56.3 ± 27.5

99.1 ± 0.4

36.3 ± 21.8

FL-AFP 6.25 μg/ml

3.5 ± 1.1

96.5 ± 1.1

30.9 ± 28.7*

98.7 ± 0.8

23.0 ± 19.8*

FL-AFP 12.5 μg/ml

10.9 ± 5.8

89.1 ± 5.8

31.4 ± 12.6*

92.4 ± 10.2

38.1 ± 14.7

FL-AFP 25 μg/ml

28.2 ± 10.2*

71.8 ± 10.2*

30.0 ± 0.2*

89.7 ± 9.8

2.5 ± 1.6*

  1. * showed significant differences compare to non treated (Tukey test, p < 0.05)
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BMC Immunology

ISSN: 1471-2172

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