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Table 2 The viability of MDDC and expression of some surface markers on the mature MDDC treated with FL-AFP at different concentration

From: Immunoregulatory effects of AFP domains on monocyte-derived dendritic cell function

  Cell viability (%) Surface marker expression (%)
  PI+ PI- CD80+ CD86+ CD83+
Non Treated 1.7 ± 1.0 98.3 ± 1.0 92.3 ± 5.8 99.4 ± 0.6 75.6 ± 24.1
FL-AFP 1.56 μg/ml 2.4 ± 1.7 97.6 ± 1.7 77.1 ± 20.1 98.8 ± 1.1 48.4 ± 21.7
FL-AFP 3.12 μg/ml 3.3 ± 2.2 96.7 ± 2.2 56.3 ± 27.5 99.1 ± 0.4 36.3 ± 21.8
FL-AFP 6.25 μg/ml 3.5 ± 1.1 96.5 ± 1.1 30.9 ± 28.7* 98.7 ± 0.8 23.0 ± 19.8*
FL-AFP 12.5 μg/ml 10.9 ± 5.8 89.1 ± 5.8 31.4 ± 12.6* 92.4 ± 10.2 38.1 ± 14.7
FL-AFP 25 μg/ml 28.2 ± 10.2* 71.8 ± 10.2* 30.0 ± 0.2* 89.7 ± 9.8 2.5 ± 1.6*
  1. * showed significant differences compare to non treated (Tukey test, p < 0.05)