Figure 1From: Host immunity in the protective response to nasal immunization with a pneumococcal antigen associated to live and heat-killed Lactobacillus caseiImmunoglobulin (Ig)A (a) and IgG (b) anti-pneumococcal protective protein A (PppA) antibodies response in nasal and bronchoalveolar lavages (NL and BAL) and serum of young mice nasally immunized with PppA and PppA associated with live (LcV) and heat-killed (LcM) Lactobacillus casei CRL 431. Results are expressed as the mean of the optical density (OD) Ā± standard deviation for each specific Ig (n = 6 mice/group at each time point). Antibodies were determined using the enzyme-linked immunosorbent assay method and samples were considered negative for the presence of specific antibodies when OD 493 < 0.1. Results are representative of two independent experiments. Significant differences with the PppA group were: P < 0.01.Back to article page