Figure 3
From: Classification of dendritic cell phenotypes from gene expression data
Top IPA generated network. The figure illustrates the graphical representation of the Ingenuity Pathway Analysis software. Each node contains comprehensive information on a gene's function, how that gene is regulated, its direct neighbours, and synonyms, Genes are represented as nodes and the biological relationship between two nodes is represented as an edge: dashed lines if relationship is indirect and continuous lines are for direct relationships. Nodes are displayed using various shapes that represent the functional class of the gene product (legend in the top left). The output of the IPA query is exploited for Biological Annotation from the IPA Knowledge Database. The top network found by IPA concerns cellular growth and proliferation and the humoral immune response. Six (grey nodes) among the ten input genes show more than one interaction (also indirect) in the network built by IPA.