Figure 7
Stimulus-dependent expression of LFA-1 and Mac-1 on neutrophils. Surface expression of LFA-1 (A) and Mac-1 (B) on bone marrow-derived neutrophils (n = 3 mice) after stimulation with CXCL1 (KC; 120 ng per 106 leukocytes/ml, 15 min), fMLP (10 μM, 106 leukocytes/ml, 15 min), or TNF-α+ fMLP (25 ng TNF-α for 3 h followed by 10 μM fMLP for 15 min in 106 leukocytes/ml) was compared to unstimulated controls (B). Representative histograms are shown from 3 separate experiments.