Mice | Venules | Diameter | Centerline Velocity | Wall shear rate | Systemic leukocyte counts | |
---|---|---|---|---|---|---|
(N) | (n) | (μm) | (μm/s) | (s-1) | (cells/μl) | |
Wild type | 6 | 6 | 30 ± 3 | 2200 ± 200 | 1800 ± 100 | 6300 ± 1000 |
RAGE -/- | 5 | 5 | 32 ± 2 | 2800 ± 200 | 2200 ± 200 | 4200 ± 700 |
Icam1 -/- | 4 | 4 | 30 ± 2 | 2400 ± 300 | 2000 ± 300 | 6400 ± 300 |
Wild type + anti-Mac-1 | 4 | 20 | 29 ± 2 | 2200 ± 100 | 2000 ± 100 | 4200 ± 200 |
Icam1-/- + anti-Mac-1 | 3 | 13 | 30 ± 2 | 2500 ± 100 | 2000 ± 100 | 4800 ± 400 |
Wild type + isotype | 3 | 10 | 30 ± 2 | 2500 ± 100 | 2100 ± 100 | 4000 ± 500 |
Wild type + anti-LFA-1 | 4 | 13 | 28 ± 2 | 2400 ± 100 | 2100 ± 100 | 4900 ± 300 |
Icam1-/- + anti-LFA-1 | 3 | 14 | 27 ± 3 | 2200 ± 200 | 2400 ± 400 | 5000 ± 300 |
Wild type + isotype | 3 | 9 | 31 ± 2 | 2500 ± 100 | 2100 ± 200 | 4600 ± 300 |
n.s. | n.s. | n.s. | n.s. |