Table 3 Hemodynamic and microvascular parameters in cremaster muscle venules during trauma induced inflammation with additional CXCL1 stimulation
Mice | Venules | Diameter | Centerline Velocity | Wall shear rate | Systemic leukocyte counts | |
|---|---|---|---|---|---|---|
(N) | (n) | (μm) | (μm/s) | (s-1) | (cells/μl) | |
Wild type | 7 | 12 | 32 ± 3 | 2200 ± 300 | 1600 ± 200 | 6300 ± 500 |
RAGE -/- | 6 | 10 | 32 ± 3 | 2000 ± 200 | 1800 ± 200 | 7400 ± 800 |
Icam-1 -/- | 4 | 11 | 28 ± 1 | 2400 ± 100 | 2100 ± 100 | 8000 ± 800 |
Wild type+ anti-LFA-1 | 4 | 10 | 28 ± 2 | 2400 ± 100 | 2200 ± 100 | 7000 ± 500 |
Wild type+ Isotype AB | 3 | 9 | 29 ± 2 | 2500 ± 200 | 2200 ± 100 | 7500 ± 600 |
n.s. | n.s. | n.s. | n.s. |