Figure 1

Antibody response in autoimmune-prone NZB/WF1. Mice immunized with phthalate-KLH Conjugate induce both anti-phthalate Antibody and anti-DNA Responses. The results represent sera of at least 5 mice tested individually using ELISA. A) anti-phthalate antibody levels after 2^nd booster immunization. B) Anti-DNA antibody levels after 2^nd booster immunization. C) anti-phthalate antibody levels after 3^rd booster immunization with antigen alone. D) Anti-DNA antibody levels after 3^rd booster immunization with antigen alone. The results represent mean from individual sera ± SD (n = 5 mice per group). The significance in experimental groups was determined relative to the group given antigen only (no adjuvant group) at the level of p ≤ 0.05.