Skip to main content

Table 2 Summary of gene expression levels obtained from whole genome microarray analysis of WT and KO lung tissue samples.

From: Vasoactive Intestinal Peptide Knockout (VIP KO) mouse model of sulfite-sensitive asthma: up-regulation of novel lung carbonyl reductase

Gene Symbol Average KO Average WT KO/WT Fold change P value
triosephosphate isomerase 1 Tpi1 1.15 0.89 1.29 0.033
quininoid dihydropteridine reductase Qdpr 0.93 1.09 0.85 0.195
pyruvate dehydrogenase Pdhb 1.05 0.95 1.10 0.065
superoxide dismutase 1 Sod1 0.82 1.11 0.74 0.017
superoxide dismutase 2 Sod2 0.92 1.04 0.88 0.041
superoxide dismutase 3 Sod3 1.09 0.98 1.11 0.543
carbonyl reductase 2 Cbr2 1.00 1.02 0.97 0.630
carbonyl reductase 3 Cbr3 1.00 1.19 0.84 0.439
carbonic anhydrase 3 Car3 1.67 0.39 4.35 0.001
glycerol-3-phosphate dehydrogenase 1 Gpd1 1.83 0.66 2.76 0.095
glycerol-3-phosphate dehydrogenase 2 Gpd2 1.15 0.88 1.30 0.009
  1. All of the above gene expression levels were confirmed by Real-Time PCR analysis (data not shown).