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Table 2 Summary of gene expression levels obtained from whole genome microarray analysis of WT and KO lung tissue samples.

From: Vasoactive Intestinal Peptide Knockout (VIP KO) mouse model of sulfite-sensitive asthma: up-regulation of novel lung carbonyl reductase

Gene

Symbol

Average KO

Average WT

KO/WT Fold change

P value

triosephosphate isomerase 1

Tpi1

1.15

0.89

1.29

0.033

quininoid dihydropteridine reductase

Qdpr

0.93

1.09

0.85

0.195

pyruvate dehydrogenase

Pdhb

1.05

0.95

1.10

0.065

superoxide dismutase 1

Sod1

0.82

1.11

0.74

0.017

superoxide dismutase 2

Sod2

0.92

1.04

0.88

0.041

superoxide dismutase 3

Sod3

1.09

0.98

1.11

0.543

carbonyl reductase 2

Cbr2

1.00

1.02

0.97

0.630

carbonyl reductase 3

Cbr3

1.00

1.19

0.84

0.439

carbonic anhydrase 3

Car3

1.67

0.39

4.35

0.001

glycerol-3-phosphate dehydrogenase 1

Gpd1

1.83

0.66

2.76

0.095

glycerol-3-phosphate dehydrogenase 2

Gpd2

1.15

0.88

1.30

0.009

  1. All of the above gene expression levels were confirmed by Real-Time PCR analysis (data not shown).