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Figure 5 | BMC Immunology

Figure 5

From: Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension

Figure 5

Accumulation of T reg cells in non-transgenic and transgenic (TgL) strains of mice at 8 to 10 week-old. The percentage (A) and absolute numbers (B) of CD4+ Foxp3+Treg cells in the lung are shown. The absolute lymphocytic number was calculated from the percentage of Treg and the total cell number. (C) The ratio of effector/memory T cells (CD4+ CD25- CD44 high CD62L low) to Fopx3+ Treg cells in the lung. A significant increase in this ratio is shown in B6.TgL strain of mice. The result represents a mean ± SD from 4 mice per each group. The results of flow cytometry (A) are representative of two independent experiments. The significant difference between the two groups was evaluated by two tailed t- test. *, p < 0.01; **, p < 0.001.

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BMC Immunology

ISSN: 1471-2172

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