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Table 2 Genetic association of PAH score in BCN2

From: Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension

Marker

Position (CM)

Mean of grade†

Mean of grade

P value‡

  

BB

BC

 

D5Mit346

1

0.51 ± 0.61 (172)

0.32 ± 0.46 (169)

0.0018 §

D5Mit381

8

0.51 ± 0.59 (178)

0.32 ± 0.46 (163)

0.0012 §

D5Mit197

36

0.46 ± 0.56 (192)

0.36 ± 0.52 (149)

0.0844

D5Mit338

59

0.45 ± 0.55 (191)

0.37 ± 0.53 (150)

0.1476

D5Mit213

70

0.41 ± 0.52 (192)

0.42 ± 0.58 (149)

0.9149

D5Mit409

83

0.42 ± 0.55 (165)

0.41 ± 0.54 (178)

0.766

  1. * Values indicate mean ± SD and the values in parenthesis denote the number of mice.
  2. † BB = B6 homozygote; BC = B6/BALB heterozygote
  3. ‡ The two-tail t-test. §, suggestive linkage [22].
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BMC Immunology

ISSN: 1471-2172

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