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Figure 7 | BMC Immunology

Figure 7

From: Autoreactive marginal zone B cells enter the follicles and interact with CD4+ T cells in lupus-prone mice

Figure 7

CD4+ T cell proliferation and activation in response to FOB or MZB cells from B6 or B6.TC mice. A. Proliferation in 5 d cultures. B. Forward scatter mean fluorescence intensity (mfi). C. Percentage of CD4+ T cells. CD69 (D) and CD62L (E) expression. All cells were gated on live CD4+ T cells. Proliferation was assessed with CFSE dilution as the percentage of CD4+ T cells in the last two cell division cycles (CSFE-low). Results are representative of two independent assays. Means and SEM and Dunnett's Multiple Comparison Tests. *: p < 0.05; **: p < 0.01, ***: p < 0.001.

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