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Figure 4 | BMC Immunology

Figure 4

From: Influence of variable domain glycosylation on anti-neutrophil cytoplasmic autoantibodies and anti-glomerular basement membrane autoantibodies

Figure 4

Comparison of effects on respiratory burst of neutrophils between non-SNA-binding IgG and SNA-binding IgG. A: Respiratory burst of neutrophils induced by anti-MPO antibodies. Mo: monoclonal mouse anti-MPO antibody. N: normal IgG. Because of limited sample volume, two patients with anti-MPO antibodies and anti-GBM antibodies (patients 11 and 16) were not included in this analysis. Open squares represent non-SNA-binding IgG; Filled squares represent SNA-binding IgG. B: Respiratory burst of neutrophils induced by anti-PR3 antibodies. Mo: monoclonal mouse anti-PR3 antibody. N: normal IgG. Open squares represent non-SNA-binding IgG; Filled squares represent SNA-binding IgG.

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