Skip to main content
Figure 5 | BMC Immunology

Figure 5

From: Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment

Figure 5

Prolactin receptor expression in MRL/lpr mice at different ages. Ten C57BL/6 and ten MRL/lpr mice were treated with metoclopramide (100 μg/100 μl) for 6 weeks [hyperprolactinaemia (HyperPRL)] or PBS (control). Splenic B cells were purified using negative selection from treated and untreated mice: at 9 and 25 weeks of age (untreated) and 15 weeks of age, mice were treated with metoclopramide or PBS (expression of the PRL receptor was determined by real-time PCR [mRNA]). The asterisks denote statistical significance between populations with the p value shown.

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us