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Figure 1 | BMC Immunology

Figure 1

From: The Tat protein of human immunodeficiency virus-1 enhances hepatitis C virus replication through interferon gamma-inducible protein-10

Figure 1

Analysis of IP-10 mRNA and HCV RNA levels in PBMCs isolated from healthy individuals, HCV mono-infected patients, and HIV-1/HCV co-infected patients. (A) Transcriptional expression of IP-10 in PBMCs isolated from HCV mono-infected patients, HIV-1/HCV co-infected patients, and healthy individuals. Data were normalized to the amount of GAPDH-specific mRNA as a reference transcript. Numbers below each patient group (e.g. n = 24) indicate the number of persons in that group. (B) Replication of HCV RNA in PBMCs isolated from patients with HCV mono-infection and HIV-1/HCV co-infection. Data were normalized to the amount of GAPDH-specific mRNA as a reference transcript. (C) Correlations between the expression of IP-10 mRNA and HCV RNA in PBMCs isolated from patients with HCV mono-infection and HIV-1/HCV co-infection. (D) Correlations between the expression of IP-10 mRNA and HCV RNA in PBMCs isolated from patients with HIV-1/HCV co-infection. Two groups of patients were analyzed for IP-10 mRNA and HCV RNA expression. Data were subjected to linear regression analysis. Correlation coefficients are indicated.

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