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Figure 4 | BMC Immunology

Figure 4

From: Tissue transglutaminase treatment leads to concentration-dependent changes in dendritic cell phenotype - implications for the role of transglutaminase in coeliac disease

Figure 4

T-cell proliferation in response to co-culture with treated DCs. Naïve T-cell proliferation was assessed following 5 days of culture with pre-treated DCs (48 h and loaded with gliadin) (n = 1). Samples include naïve T-cell cultured in a mixed lymphocyte reaction (MLR) and treated DCs, and naïve T cells in single culture. Absorbance values for DCs in single culture were subtracted to give the values shown. Sample treatments correspond to untreated (CTRL) and TG-2 activity defined as 0.039 U/mL (TG-2 [high]), 0.0036 U/mL (TG-2 [mid]) or 0.00022 U/mL (TG-2 [low]).

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