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Figure 5 | BMC Immunology

Figure 5

From: Tissue transglutaminase treatment leads to concentration-dependent changes in dendritic cell phenotype - implications for the role of transglutaminase in coeliac disease

Figure 5

Cytokine expression profile of naïve T cells in co-culture with dendritic cells. Cytokine production from co-culture of naïve T cells and DCs following treatment with TG as previously described (n = 1). Concentrations (pg/ml) of IFN-γ (A), IL-13 (B) and IL-10 (C) in supernatant following co-culture of naïve T cells with DCs in a mixed lymphocyte reaction (MLR) (upper panel) or co-culture of naïve T cells with DCs which had been loaded with gliadin. Also depicted is cytokine production by naïve Tcells and DCs in single culture. Treatments correspond to untreated (CTRL), 1% BSA and TG-2 activity defined as 0.039 U/mL (TG-2 [high]), 0.0036 U/mL (TG-2 [mid]) or 0.00022 U/mL (TG-2 [low]).

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BMC Immunology

ISSN: 1471-2172

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