Figure 2

Distribution of¹²⁵I-Stx2 in body fluids following 3 h, 1 and 2 days of¹²⁵I-Stx2 injection. Mice were given intraperitoneally PBS or 30 μg of HuMAbs 5C12 or 5H8 followed 4 hours later with intravenous administration of 100 ng of ¹²⁵I-Stx2. Distribution of ¹²⁵I-Stx2 in body fluids was determined following 3 h, day 1 and day 2 of ¹²⁵I-Stx2 injection, and expressed as “% injected dose (ID)/ml fluid”. Bars with different letters (a and b) within a body fluid at a particular sampling time point indicate differences are statistically significant (p < 0.05) among those treatment groups. Bars with same letter within a body fluid at a particular sampling time point indicate differences are not statistically significant among those treatment groups.