Table 2 Predicted effects of LT on monocyte function.1
Gene | Microarray | Effects |
|---|---|---|
RGS-14 | 5.61 | Blockade of monocyte maturation to dendritic cells, inhibition of chemotaxis |
CXCR2 | 5.04 | Increased monocyte transendothelial migration into tissues |
HPSE | -2.58 | Diminished inflammatory response |
CCR5 | -2.33 | Reduced responsiveness to the inflammatory mediators RANTES, MIP1 beta |
ILIR2 | -12.5 | Increased IL1 alpha responsiveness and increased fever |