Figure 2

Deficiency of γδ T cells leads to increased bacteria burden. (A) Mice were inoculated with sub-lethal SA 75 strain (5x10⁸CFU,n = 6/group/time point). Bacterial burden in lung and spleen were determined at 24 and 48 hours following pulmonary infection with S.aureus. Each dot represents the bacterial count of the respective organ of a single animal. The line represents the median of each group. (B) Survival curve of WT(n = 8)and TCR-δ^−/− (n = 9) mice after intranasally inoculated with 5x10⁹ CFU bacteria. p = 0.269 for infected TCR-δ^−/− versus WT mice.