DSS treatment induced quantitative changes in colonic epithelial cell populations. Colonic sections were collected from 3 or 1% DSS-treated, wild-type mice on days 0, 7, and 14. 50 crypts from three mice at each time point for each DSS treatment (150 crypts at each treatment time point) were analyzed for: (A) number of Ki-67+ cells per colonic crypt, (B) colonic crypt length, (C) goblet cells per colonic crypt, and (D) number of TUNEL + cells per colonic crypt. Bars represent mean ± standard error of the means. Values were not significant unless indicated: * p < 0.05, ** p < 0.01, *** p < 0.001; ANOVA.