Figure 2

(A) percentage of CD26+ overall white blood cells, (B) percentage of CD26+ lymphocytes, (C) mean fluorescence intensity (MFI) of CD26 expression on lymphocytes and (D) percentage of lymphocytes, in healthy controls (C), in people with vitiligo (V), in patients with melanoma (M), and in patients with other malignant skin tumors (MST) or benign skin changes (BS). Xav+/−SD are cut off values obtained from healthy controls. Green circles with borders represent melanoma patients without metastases, while green circles without borders represent melanoma patients with metastatic disease. There is a statistically significant decrease in the percentage of CD26+ overall white blood cells, (Wilcoxon rank sum test with continuity correction: W = 679.5; p < 0.00006), as well as in the percentage of lymphocytes (Wilcoxon rank sum test with continuity correction: W = 644.5; p < 0.00003) in patients with melanoma compared to healthy controls.