Figure 6

Shannon entropy values (top panels) and amino acid (AA) frequencies (bottom panels) of unique CDR3 sequences of representative lengths from all repertoires examined. A: CDR3 lengths of 6 AAs (n = 985); B: CDR3 lengths of 15 AAs (n = 523); C: CDR3 lengths of 22 AAs (n = 1,363); D: CDR3 lengths of 28 AAs (n = 524). X-axis values follow the IMGT numbering standard for CDR3 with each bar representing 100% of the amino acids identified at that position. Amino acids are grouped according to hydrophobicity with charged amino acids at the bottom and hydrophobic amino acids at the top.