Figure 8

Effect of lactobacilli on lung dendritic cells activation induced by the nasal administration of the viral pathogen-associated molecular pattern poly(I:C). Effect of Lactobacillus rhamnosus CRL1505 (Lr1505) or L. rhamnosus CRL1506 (Lr1506) administration on the number of pulmonary CD11c⁺CD11b^lowCD103⁺ and CD11c⁺CD11b^highCD103^- dendritic cells after the challenge with poly(I:C) (A). Effect of Lr1505 or Lr1506 administration on the expression of MHC-II, IFN-γ and IL-12 in pulmonary CD11c⁺CD11b^lowCD103⁺ and CD11c⁺CD11b^highCD103^- dendritic cells after the challenge with poly(I:C) (B). The results represent data from three independent experiments. Significant differences between lactobacilli-treated and control groups * (P < 0.05).